Ryan Hallett, Ph.D.
Ryan received a B.S. in Chemistry from the University of Florida before completing his PhD in Biochemistry and Biophysics in Brian Kuhlman’s laboratory at UNC-Chapel Hill. During his doctoral work, Ryan specialized in engineering and improving light-activated protein research tools that are currently being used by over 30 labs across the country. Ryan brings skilled design and characterization of protein interactions, a strong background of reagent development, and an entrepreneurial spirit to the Dualogics team.
Tim Jacobs, Ph.D.
Tim received his B.S. in Bioinformatics at the University of Buffalo before completing his Ph.D. in Bioinformatics and Computational Biology under Brian Kuhlman at UNC-Chapel Hill. Tim has worked primarily on designing proteins and affinity reagents through a combination of novel computational algorithms and high-throughput screening methods. Tim excels at technical communication and provides Dualogics with valuable expertise in the modeling of protein structure.
Brian Kuhlman, Ph.D.
Brian has been a professor in the Biochemistry and Biophysics department at UNC Chapel Hill since 2002. During his postdoc with David Baker, Brian worked as one of the initial developers of the Rosetta molecular modeling suite, resulting in the design of a previously unobserved protein fold. Brian’s lab specializes in the design and engineering of proteins and protein interfaces. His work has led to multiple patents related to protein engineering, including the designed protein interface used to generate OrthoMab bispecific antibodies. Brian enjoys solving complex protein design problems with creative solutions. Brian serves as head of scientific advisory board at Dualogics, imparting his 20 years of protein engineering experience, and creativity in solving complex protein design problems.
Andrew Leaver-Fay, Ph.D.
Andrew also received his postdoctoral training under David Baker, where he led the complete refactoring of the Rosetta molecular modeling suite. Andrew’s talent for algorithm development has resulted in software that continues to enable many of the high-profile successes in the field of protein design, including the multi-state design algorithm used for the creation of OrthoMab bispecific antibodies. Andrew’s strong quantitative skill set and experience with antibody engineering make him an excellent addition to Dualogics’ Scientific Advisory Board.
Don Rose, Ph.D.
Don received his Ph.D. in Analytical Chemistry and B.S. in Nutrition from the University of North Carolina. Don is the Director of UNC’s Carolina KickStart Program, which provides support the commercialization of biomedical technologies developed at UNC. Prior to leading KickStart, Don held senior leadership roles at a number of life science startups, and served as a general partner at Catalysta Partners (now Hatteras Venture Partners). Don’s extensive experience in the life science startup community and background in analytical chemistry make him an ideal member of the Dualogics team.